The USA will miss their third straight Olympic Men's football tournament after losing 2-1 to Honduras in their qualification game.
Gabriel Jesus, Roberto Firmino and Philippe Coutinho were on target as Brazil geared up for the Copa America with a 7-0 rout.
Alexis Sanchez scored for the second game in a row as Chile beat Honduras 4-1 in a friendly on Tuesday.
Mario Balotelli took just 21 minutes to find the net for Italy on his return to the side as they beat Saudi Arabia 2-1 in a friendly on Monday.
Mile Jedinak scored two penalties and forced an own goal as Australia reached next year's World Cup at the expense of Honduras.
Australia will fancy their chances of going to next year's World Cup after drawing the first leg of their play-off clash in Honduras.